DISCOVERIES

KORUPENSAMINES

Source Plant

The Korupensamines have been isolated from a sample of Ancistrocladus korupensis D. W. Thomas & Gereau (Ancistrocladaceae), a newly described species of liana originally collected in the region of Korup National Park in Cameroon in 1987 (Thomas 6889).

Chemical Structure

 Korupensamine A 

Activity

The korupensamines have exhibited anti-malarial activity.

References

Hallock, Y.F., K.P. Manfredi, J.W. Blunt, J.H. Cardellina II, M. Achaeffer, G. Bringmann, A.Y. Lee, J. Clardy, G. Francois, and M.R. Boyd. 1991. Korupensamines A-D, Novel antimalarial alkaloids from Ancistrocladus korupensis. J. Org. Chem. 59:6349-6355.

Thomas, D.W. and R.E. Gereau. 1993. Ancistrocladus korupensis (Ancistrocladaceae): a new species of liana from Cameroon. Novon 3:494-498.

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