DISCOVERIES

TRITERPENES

Source Plant

A series of triterpenes was isloated from Maprounea africana Muell.-Arg. originally collected in the Park Manovo-Gounda-St. Floris in the Central African Republic in May of 1987 (Fay 8002) and Maprounea membranacea Pax & K. Hoffman originally collected near Bonambwasse village, 5 km south of Dibombari, in Littoral Province of Cameroon in February of 1988 (Nemba et al. 794). Four of the triterpenes were found to be novel natural products.

Chemical Structure

 Triterpenes

Activity

Anti-HIV activity was reported from extracts of two species of Maprounea.

Reference

Beutler, J.A., Y. Kashman, M. Tischler, J.H. Cardellina II, G.N. Gray, M.J. Currens, M.E. Wall, M.C. Wani, and M.R. Boyd. 1995. A reinvestigation of Maprounea triterpenes. J. Nat. Prod. 58:1039-1056.

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